<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with Wdesk from Workiva-->
<!--Copyright 2020 Workiva-->
<!--r:4b646be3-19b8-49cd-83c4-094f26fc88c3,g:8feff1be-4137-4c91-a14c-e10a49d33a8a-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.wynnresorts.com/role/DocumentandEntityInformation" xlink:type="simple" xlink:href="wynn-20200819.xsd#DocumentandEntityInformation"/>
  <link:presentationLink xlink:role="http://www.wynnresorts.com/role/DocumentandEntityInformation" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_wynn_DEIAbstract_864ba8f2-502b-4809-a0e5-c76ae677dbc6" xlink:href="wynn-20200819.xsd#wynn_DEIAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_f164491f-ca5d-4179-8123-5f62a70cc3a3" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_Security12bTitle"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_864ba8f2-502b-4809-a0e5-c76ae677dbc6" xlink:to="loc_dei_Security12bTitle_f164491f-ca5d-4179-8123-5f62a70cc3a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_65444e46-9ec1-48b2-827d-bdbd0ba4d320" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_864ba8f2-502b-4809-a0e5-c76ae677dbc6" xlink:to="loc_dei_EntityIncorporationStateCountryCode_65444e46-9ec1-48b2-827d-bdbd0ba4d320" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_0d3df801-33e0-47db-9486-e7bd2b17fbea" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityFileNumber"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_864ba8f2-502b-4809-a0e5-c76ae677dbc6" xlink:to="loc_dei_EntityFileNumber_0d3df801-33e0-47db-9486-e7bd2b17fbea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_049645dd-d65a-4887-98a1-69e9a217b070" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_864ba8f2-502b-4809-a0e5-c76ae677dbc6" xlink:to="loc_dei_EntityTaxIdentificationNumber_049645dd-d65a-4887-98a1-69e9a217b070" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_50c94ece-4783-4ccf-936f-872e0be51d26" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressAddressLine1"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_864ba8f2-502b-4809-a0e5-c76ae677dbc6" xlink:to="loc_dei_EntityAddressAddressLine1_50c94ece-4783-4ccf-936f-872e0be51d26" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_ef92c259-3f80-4a69-a995-894208112ae4" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressCityOrTown"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_864ba8f2-502b-4809-a0e5-c76ae677dbc6" xlink:to="loc_dei_EntityAddressCityOrTown_ef92c259-3f80-4a69-a995-894208112ae4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_85821af7-970e-4e32-bc7b-ade4c3be028c" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressStateOrProvince"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_864ba8f2-502b-4809-a0e5-c76ae677dbc6" xlink:to="loc_dei_EntityAddressStateOrProvince_85821af7-970e-4e32-bc7b-ade4c3be028c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_0b4a65b9-6fca-4df9-b88f-68abb4cf861c" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentType"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_864ba8f2-502b-4809-a0e5-c76ae677dbc6" xlink:to="loc_dei_DocumentType_0b4a65b9-6fca-4df9-b88f-68abb4cf861c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_5aaa0221-d0fa-4ea1-a9c2-6dd27f4ec337" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityRegistrantName"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_864ba8f2-502b-4809-a0e5-c76ae677dbc6" xlink:to="loc_dei_EntityRegistrantName_5aaa0221-d0fa-4ea1-a9c2-6dd27f4ec337" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_818ad198-0263-4840-b9c5-4ad1e40b4aae" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityCentralIndexKey"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_864ba8f2-502b-4809-a0e5-c76ae677dbc6" xlink:to="loc_dei_EntityCentralIndexKey_818ad198-0263-4840-b9c5-4ad1e40b4aae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_07b6d426-6d37-4b51-adf8-79d91051c622" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentPeriodEndDate"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_864ba8f2-502b-4809-a0e5-c76ae677dbc6" xlink:to="loc_dei_DocumentPeriodEndDate_07b6d426-6d37-4b51-adf8-79d91051c622" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_ee24e0f5-5f10-492e-96d1-bbf1a076b43a" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressPostalZipCode"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_864ba8f2-502b-4809-a0e5-c76ae677dbc6" xlink:to="loc_dei_EntityAddressPostalZipCode_ee24e0f5-5f10-492e-96d1-bbf1a076b43a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_c992bcbe-1d8c-408b-a5f5-ac541fa73668" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CityAreaCode"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_864ba8f2-502b-4809-a0e5-c76ae677dbc6" xlink:to="loc_dei_CityAreaCode_c992bcbe-1d8c-408b-a5f5-ac541fa73668" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_72bf96c6-92b2-4ca1-9003-fa2f48fd1595" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_LocalPhoneNumber"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_864ba8f2-502b-4809-a0e5-c76ae677dbc6" xlink:to="loc_dei_LocalPhoneNumber_72bf96c6-92b2-4ca1-9003-fa2f48fd1595" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_WrittenCommunications_12f31391-4b63-4e9d-972b-96e0604eb5fb" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_WrittenCommunications"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_864ba8f2-502b-4809-a0e5-c76ae677dbc6" xlink:to="loc_dei_WrittenCommunications_12f31391-4b63-4e9d-972b-96e0604eb5fb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_8c16b28b-6f34-42ac-bb23-4718f04013b9" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_TradingSymbol"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_864ba8f2-502b-4809-a0e5-c76ae677dbc6" xlink:to="loc_dei_TradingSymbol_8c16b28b-6f34-42ac-bb23-4718f04013b9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_9fcff74a-99e4-424e-81d1-e6f9c1d86da5" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_SecurityExchangeName"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_864ba8f2-502b-4809-a0e5-c76ae677dbc6" xlink:to="loc_dei_SecurityExchangeName_9fcff74a-99e4-424e-81d1-e6f9c1d86da5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SolicitingMaterial_342d3435-9d6b-48f1-a89a-dd8961e4ab76" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_SolicitingMaterial"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_864ba8f2-502b-4809-a0e5-c76ae677dbc6" xlink:to="loc_dei_SolicitingMaterial_342d3435-9d6b-48f1-a89a-dd8961e4ab76" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementTenderOffer_b7e35bdb-cc3a-4ecf-b75e-534e7f5997db" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_PreCommencementTenderOffer"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_864ba8f2-502b-4809-a0e5-c76ae677dbc6" xlink:to="loc_dei_PreCommencementTenderOffer_b7e35bdb-cc3a-4ecf-b75e-534e7f5997db" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementIssuerTenderOffer_4d2bb7ff-04bd-4d4e-b442-128818d016c6" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_PreCommencementIssuerTenderOffer"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_864ba8f2-502b-4809-a0e5-c76ae677dbc6" xlink:to="loc_dei_PreCommencementIssuerTenderOffer_4d2bb7ff-04bd-4d4e-b442-128818d016c6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_d7232c5e-4a0e-4065-a4e8-40d30acf5d14" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_864ba8f2-502b-4809-a0e5-c76ae677dbc6" xlink:to="loc_dei_EntityEmergingGrowthCompany_d7232c5e-4a0e-4065-a4e8-40d30acf5d14" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_dc5ca582-1828-4782-aadc-f624e7c00b28" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_AmendmentFlag"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_864ba8f2-502b-4809-a0e5-c76ae677dbc6" xlink:to="loc_dei_AmendmentFlag_dc5ca582-1828-4782-aadc-f624e7c00b28" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
</link:linkbase>
