<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2025 Workiva-->
<!--r:ef4ce345-850d-44f3-9c61-3a1281ab1eca,g:937e314c-7bfd-4154-b4e4-7f86708b6747-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.wynnresorts.com/role/DocumentandEntityInformation" xlink:type="simple" xlink:href="wynn-20250213.xsd#DocumentandEntityInformation"/>
  <link:presentationLink xlink:role="http://www.wynnresorts.com/role/DocumentandEntityInformation" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract_3f9dbf8b-a244-4aeb-8609-ee638c54e523" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_CoverAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_df065777-46d9-4f8a-8765-030bc5b83c4f" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentType"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3f9dbf8b-a244-4aeb-8609-ee638c54e523" xlink:to="loc_dei_DocumentType_df065777-46d9-4f8a-8765-030bc5b83c4f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_1a09c42a-81a9-4c5e-bbba-a6badf7c304e" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentPeriodEndDate"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3f9dbf8b-a244-4aeb-8609-ee638c54e523" xlink:to="loc_dei_DocumentPeriodEndDate_1a09c42a-81a9-4c5e-bbba-a6badf7c304e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_1eb132fa-a1d8-40ce-aec5-1e8eb41725d7" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityRegistrantName"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3f9dbf8b-a244-4aeb-8609-ee638c54e523" xlink:to="loc_dei_EntityRegistrantName_1eb132fa-a1d8-40ce-aec5-1e8eb41725d7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_65933c08-7f7d-437c-b903-47d604bc4447" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3f9dbf8b-a244-4aeb-8609-ee638c54e523" xlink:to="loc_dei_EntityIncorporationStateCountryCode_65933c08-7f7d-437c-b903-47d604bc4447" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_d32ceae6-4ae7-4d17-b5dc-dfd96295e4f3" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityFileNumber"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3f9dbf8b-a244-4aeb-8609-ee638c54e523" xlink:to="loc_dei_EntityFileNumber_d32ceae6-4ae7-4d17-b5dc-dfd96295e4f3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_22aadba8-e1fe-463d-94a7-1275d0a0728c" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3f9dbf8b-a244-4aeb-8609-ee638c54e523" xlink:to="loc_dei_EntityTaxIdentificationNumber_22aadba8-e1fe-463d-94a7-1275d0a0728c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_9c542879-163c-4ae3-b73a-066c06b0a33f" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressAddressLine1"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3f9dbf8b-a244-4aeb-8609-ee638c54e523" xlink:to="loc_dei_EntityAddressAddressLine1_9c542879-163c-4ae3-b73a-066c06b0a33f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_51fad6c0-019c-45c6-a337-977c447d881e" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressCityOrTown"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3f9dbf8b-a244-4aeb-8609-ee638c54e523" xlink:to="loc_dei_EntityAddressCityOrTown_51fad6c0-019c-45c6-a337-977c447d881e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_2258b069-56c6-4830-a480-d2ada3675b5f" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressStateOrProvince"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3f9dbf8b-a244-4aeb-8609-ee638c54e523" xlink:to="loc_dei_EntityAddressStateOrProvince_2258b069-56c6-4830-a480-d2ada3675b5f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_6d112866-0504-456f-a445-0f1ef4b2a41a" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressPostalZipCode"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3f9dbf8b-a244-4aeb-8609-ee638c54e523" xlink:to="loc_dei_EntityAddressPostalZipCode_6d112866-0504-456f-a445-0f1ef4b2a41a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_8b94f97d-7d46-474b-a1d4-623b1d71f8b5" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_CityAreaCode"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3f9dbf8b-a244-4aeb-8609-ee638c54e523" xlink:to="loc_dei_CityAreaCode_8b94f97d-7d46-474b-a1d4-623b1d71f8b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_4de144cf-90d2-4992-808e-b558005b05f0" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_LocalPhoneNumber"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3f9dbf8b-a244-4aeb-8609-ee638c54e523" xlink:to="loc_dei_LocalPhoneNumber_4de144cf-90d2-4992-808e-b558005b05f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_b01d7c56-8047-40bd-a879-548b3b4b86fd" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_Security12bTitle"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3f9dbf8b-a244-4aeb-8609-ee638c54e523" xlink:to="loc_dei_Security12bTitle_b01d7c56-8047-40bd-a879-548b3b4b86fd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_e3baeeb9-149a-4b7c-ac3d-c407974394a9" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_TradingSymbol"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3f9dbf8b-a244-4aeb-8609-ee638c54e523" xlink:to="loc_dei_TradingSymbol_e3baeeb9-149a-4b7c-ac3d-c407974394a9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_57a94b4e-5211-416b-95ab-5c218645024c" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_SecurityExchangeName"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3f9dbf8b-a244-4aeb-8609-ee638c54e523" xlink:to="loc_dei_SecurityExchangeName_57a94b4e-5211-416b-95ab-5c218645024c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_WrittenCommunications_e139bf74-59d6-44d3-8b96-ee573e78d299" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_WrittenCommunications"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3f9dbf8b-a244-4aeb-8609-ee638c54e523" xlink:to="loc_dei_WrittenCommunications_e139bf74-59d6-44d3-8b96-ee573e78d299" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SolicitingMaterial_3237c219-d47c-4acf-a412-67eb737d21ce" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_SolicitingMaterial"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3f9dbf8b-a244-4aeb-8609-ee638c54e523" xlink:to="loc_dei_SolicitingMaterial_3237c219-d47c-4acf-a412-67eb737d21ce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementTenderOffer_85427129-0fd4-4d9e-ac2d-3d682595f241" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_PreCommencementTenderOffer"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3f9dbf8b-a244-4aeb-8609-ee638c54e523" xlink:to="loc_dei_PreCommencementTenderOffer_85427129-0fd4-4d9e-ac2d-3d682595f241" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementIssuerTenderOffer_f98faca1-12a7-4bf0-90af-db3fa9434a1d" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_PreCommencementIssuerTenderOffer"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3f9dbf8b-a244-4aeb-8609-ee638c54e523" xlink:to="loc_dei_PreCommencementIssuerTenderOffer_f98faca1-12a7-4bf0-90af-db3fa9434a1d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_6ce56a44-f78b-4a07-92f2-0cf88766187d" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3f9dbf8b-a244-4aeb-8609-ee638c54e523" xlink:to="loc_dei_EntityEmergingGrowthCompany_6ce56a44-f78b-4a07-92f2-0cf88766187d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_263f3d87-5237-4bb9-b11d-e0f11b5d6698" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_AmendmentFlag"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3f9dbf8b-a244-4aeb-8609-ee638c54e523" xlink:to="loc_dei_AmendmentFlag_263f3d87-5237-4bb9-b11d-e0f11b5d6698" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_19475ec9-c19a-4d4a-968d-911d61859cef" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityCentralIndexKey"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3f9dbf8b-a244-4aeb-8609-ee638c54e523" xlink:to="loc_dei_EntityCentralIndexKey_19475ec9-c19a-4d4a-968d-911d61859cef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
</link:linkbase>
