<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with Wdesk from Workiva-->
<!--Copyright 2020 Workiva-->
<!--r:56ac0686-27db-4adf-b9ea-f29ec6013114,g:b6212633-4d03-44cb-8eda-817566b87a7c-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.wynnresorts.com/role/Cover" xlink:type="simple" xlink:href="wynn-20200206.xsd#Cover"/>
  <link:presentationLink xlink:role="http://www.wynnresorts.com/role/Cover" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract_3526424e-e7d1-4b30-95bf-feaab9a83044" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_6033e772-ccb0-4f56-a664-9b86fa034269" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentType"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3526424e-e7d1-4b30-95bf-feaab9a83044" xlink:to="loc_dei_DocumentType_6033e772-ccb0-4f56-a664-9b86fa034269" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_ed46fee0-f5bd-495e-ae68-d7ab2794190f" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentPeriodEndDate"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3526424e-e7d1-4b30-95bf-feaab9a83044" xlink:to="loc_dei_DocumentPeriodEndDate_ed46fee0-f5bd-495e-ae68-d7ab2794190f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_d0b600e1-d199-4960-887f-57640166954d" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityRegistrantName"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3526424e-e7d1-4b30-95bf-feaab9a83044" xlink:to="loc_dei_EntityRegistrantName_d0b600e1-d199-4960-887f-57640166954d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_dc440c8a-7095-4d3b-8bfc-fd978a28192b" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3526424e-e7d1-4b30-95bf-feaab9a83044" xlink:to="loc_dei_EntityIncorporationStateCountryCode_dc440c8a-7095-4d3b-8bfc-fd978a28192b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_89928efc-7ee8-4a1d-b902-59293a7ec426" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityFileNumber"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3526424e-e7d1-4b30-95bf-feaab9a83044" xlink:to="loc_dei_EntityFileNumber_89928efc-7ee8-4a1d-b902-59293a7ec426" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_d60cf4ae-c90c-4432-b06a-ff56934937ec" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3526424e-e7d1-4b30-95bf-feaab9a83044" xlink:to="loc_dei_EntityTaxIdentificationNumber_d60cf4ae-c90c-4432-b06a-ff56934937ec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_ee828c2d-bed3-42b6-9edd-4d8e5e6980d7" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressAddressLine1"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3526424e-e7d1-4b30-95bf-feaab9a83044" xlink:to="loc_dei_EntityAddressAddressLine1_ee828c2d-bed3-42b6-9edd-4d8e5e6980d7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_506cccb6-6abd-4ad9-a0b7-a58e25b901a5" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressCityOrTown"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3526424e-e7d1-4b30-95bf-feaab9a83044" xlink:to="loc_dei_EntityAddressCityOrTown_506cccb6-6abd-4ad9-a0b7-a58e25b901a5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_e62098a5-40ed-46ac-b9cb-b13447113315" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressStateOrProvince"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3526424e-e7d1-4b30-95bf-feaab9a83044" xlink:to="loc_dei_EntityAddressStateOrProvince_e62098a5-40ed-46ac-b9cb-b13447113315" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_1215bf16-247a-4289-af9a-49455fd1fc6f" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressPostalZipCode"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3526424e-e7d1-4b30-95bf-feaab9a83044" xlink:to="loc_dei_EntityAddressPostalZipCode_1215bf16-247a-4289-af9a-49455fd1fc6f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_d0d1b277-52d8-499c-a75e-62188035fc00" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CityAreaCode"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3526424e-e7d1-4b30-95bf-feaab9a83044" xlink:to="loc_dei_CityAreaCode_d0d1b277-52d8-499c-a75e-62188035fc00" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_7fa26515-4b3b-40a6-8436-fd21c0e6ce85" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_LocalPhoneNumber"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3526424e-e7d1-4b30-95bf-feaab9a83044" xlink:to="loc_dei_LocalPhoneNumber_7fa26515-4b3b-40a6-8436-fd21c0e6ce85" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_a8ebcd5f-4b11-45dd-8037-16ae465ebb46" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_Security12bTitle"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3526424e-e7d1-4b30-95bf-feaab9a83044" xlink:to="loc_dei_Security12bTitle_a8ebcd5f-4b11-45dd-8037-16ae465ebb46" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_05b75805-443b-4d0e-ab9d-b910b92a1f9e" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_TradingSymbol"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3526424e-e7d1-4b30-95bf-feaab9a83044" xlink:to="loc_dei_TradingSymbol_05b75805-443b-4d0e-ab9d-b910b92a1f9e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_b5c0f511-f791-49a7-9747-ab80e465e385" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_SecurityExchangeName"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3526424e-e7d1-4b30-95bf-feaab9a83044" xlink:to="loc_dei_SecurityExchangeName_b5c0f511-f791-49a7-9747-ab80e465e385" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_WrittenCommunications_1d24b234-6a02-4d67-a5fd-4a84bfd5a7e6" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_WrittenCommunications"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3526424e-e7d1-4b30-95bf-feaab9a83044" xlink:to="loc_dei_WrittenCommunications_1d24b234-6a02-4d67-a5fd-4a84bfd5a7e6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SolicitingMaterial_35a3538c-6f7c-4381-a685-9febf0d09ed1" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_SolicitingMaterial"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3526424e-e7d1-4b30-95bf-feaab9a83044" xlink:to="loc_dei_SolicitingMaterial_35a3538c-6f7c-4381-a685-9febf0d09ed1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementTenderOffer_717518f1-4b24-4d70-aadf-2ede8c28b75b" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_PreCommencementTenderOffer"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3526424e-e7d1-4b30-95bf-feaab9a83044" xlink:to="loc_dei_PreCommencementTenderOffer_717518f1-4b24-4d70-aadf-2ede8c28b75b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementIssuerTenderOffer_6f7a33f9-f86e-4a25-b99e-21da46ed6bb4" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_PreCommencementIssuerTenderOffer"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3526424e-e7d1-4b30-95bf-feaab9a83044" xlink:to="loc_dei_PreCommencementIssuerTenderOffer_6f7a33f9-f86e-4a25-b99e-21da46ed6bb4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_32de729c-5680-4487-9a31-0107c31c2197" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3526424e-e7d1-4b30-95bf-feaab9a83044" xlink:to="loc_dei_EntityEmergingGrowthCompany_32de729c-5680-4487-9a31-0107c31c2197" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_ee95d1df-752d-44a3-9a33-85dfa1c41c44" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityCentralIndexKey"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3526424e-e7d1-4b30-95bf-feaab9a83044" xlink:to="loc_dei_EntityCentralIndexKey_ee95d1df-752d-44a3-9a33-85dfa1c41c44" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_f88f2934-062e-46d6-924b-cc4338c6141c" xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_AmendmentFlag"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_3526424e-e7d1-4b30-95bf-feaab9a83044" xlink:to="loc_dei_AmendmentFlag_f88f2934-062e-46d6-924b-cc4338c6141c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
</link:linkbase>
