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  <xs:element id="wynn_WynnInteractiveLtdMember" abstract="true" name="WynnInteractiveLtdMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="wynn_WynnLasVegasLLCandWynnLasVegasCapitalCorpMember" abstract="true" name="WynnLasVegasLLCandWynnLasVegasCapitalCorpMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="wynn_DebtInstrumentEarlyTenderPremium" abstract="false" name="DebtInstrumentEarlyTenderPremium" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="wynn_HongKongInterbankOfferedRateMember" abstract="true" name="HongKongInterbankOfferedRateMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="wynn_GeneralAndAdministrativeMember" abstract="true" name="GeneralAndAdministrativeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="wynn_RetailTermLoanAgreementMember" abstract="true" name="RetailTermLoanAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="wynn_SeniorTermLoanFacilityDue2027Member" abstract="true" name="SeniorTermLoanFacilityDue2027Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="wynn_WMCaymanIMember" abstract="true" name="WMCaymanIMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="wynn_AssumedConversionOfWMLConvertibleBonds" abstract="false" name="AssumedConversionOfWMLConvertibleBonds" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="wynn_OtherCommitmentVariablePortion" abstract="false" name="OtherCommitmentVariablePortion" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="wynn_NoncontrollingInterestTransactionsWithSubsidiaryMinorityShareholdersShares" abstract="false" name="NoncontrollingInterestTransactionsWithSubsidiaryMinorityShareholdersShares" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="wynn_Casinooutstandingchipsandfrontmoneydeposits" abstract="false" name="Casinooutstandingchipsandfrontmoneydeposits" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="wynn_CommonStockSharesReturned" abstract="false" name="CommonStockSharesReturned" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="wynn_IncreaseDecreaseInInventoriesPrepaidExpensesAndOtherCurrentAssets" abstract="false" name="IncreaseDecreaseInInventoriesPrepaidExpensesAndOtherCurrentAssets" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="wynn_ProceedsFromIssuanceOfSubsidiaryCommonStock" abstract="false" name="ProceedsFromIssuanceOfSubsidiaryCommonStock" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="wynn_GamingTaxesPolicyPolicyTextBlock" abstract="false" name="GamingTaxesPolicyPolicyTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:textBlockItemType"/>
  <xs:element id="wynn_SevenAndOneOverEightPercentageSeniorNotesDue2031Member" abstract="true" name="SevenAndOneOverEightPercentageSeniorNotesDue2031Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="wynn_LineOfCreditFacilityCommitmentNotExtended" abstract="false" name="LineOfCreditFacilityCommitmentNotExtended" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="wynn_CrownAcquisitionsIncMember" abstract="true" name="CrownAcquisitionsIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="wynn_MassachusettsGamingLicenseMember" abstract="true" name="MassachusettsGamingLicenseMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="wynn_LossesOnExtinguishmentOfDebt" abstract="false" name="LossesOnExtinguishmentOfDebt" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="wynn_OtherCommitmentScenarioThreeMember" abstract="true" name="OtherCommitmentScenarioThreeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="wynn_WynnMacauSAMember" abstract="true" name="WynnMacauSAMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="wynn_NoncontrollingInterestTransactionsWithSubsidiaryMinorityShareholdersValue" abstract="false" name="NoncontrollingInterestTransactionsWithSubsidiaryMinorityShareholdersValue" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="wynn_EarningsPerShareBasicAndDilutedEPSAbstract" abstract="true" name="EarningsPerShareBasicAndDilutedEPSAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="wynn_FiveAndOneOverFourPercentageSeniorNotesDueMay152027Member" abstract="true" name="FiveAndOneOverFourPercentageSeniorNotesDueMay152027Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="wynn_OtherCommitmentScenarioAxis" abstract="true" name="OtherCommitmentScenarioAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="wynn_RetailJointVentureMember" abstract="true" name="RetailJointVentureMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="wynn_WynnPalaceMember" abstract="true" name="WynnPalaceMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="wynn_WMCaymanIIRevolverDue2025Member" abstract="true" name="WMCaymanIIRevolverDue2025Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="wynn_HIBORMember" abstract="true" name="HIBORMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="wynn_IntangibleAssetsOtherLiabilitiesIncurred" abstract="false" name="IntangibleAssetsOtherLiabilitiesIncurred" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="wynn_OtherCommitmentScenarioDomain" abstract="true" name="OtherCommitmentScenarioDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="wynn_IntangibleAssetsOtherLiabilitiesIncurredGamingPremium" abstract="false" name="IntangibleAssetsOtherLiabilitiesIncurredGamingPremium" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="wynn_BetbullTransactionMember" abstract="true" name="BetbullTransactionMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="wynn_WeightedAverageNumberOfSharesOutstandingBasicAndDilutedAbstract" abstract="true" name="WeightedAverageNumberOfSharesOutstandingBasicAndDilutedAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="wynn_Changeinothergamingrelatedliabilities" abstract="false" name="Changeinothergamingrelatedliabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="wynn_RetailLeasesAndOtherMember" abstract="true" name="RetailLeasesAndOtherMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="wynn_Othergamingrelatedliabilities" abstract="false" name="Othergamingrelatedliabilities" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="wynn_Changeinadvancedroomdepositsandticketsales" abstract="false" name="Changeinadvancedroomdepositsandticketsales" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="wynn_FinancialLiabilityRelatedToGamingConcession" abstract="false" name="FinancialLiabilityRelatedToGamingConcession" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="wynn_GamingTaxExpenses" abstract="false" name="GamingTaxExpenses" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="wynn_OtherCommitmentToBePaidYearsFourThroughTen" abstract="false" name="OtherCommitmentToBePaidYearsFourThroughTen" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
</xs:schema>
