<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2024 Workiva-->
<!--r:9ecf2f34-8e17-4d1b-84d6-c7aaef3df6e2,g:bd198205-54f4-4e64-a637-2ed032b0978e-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.wynnresorts.com/role/DocumentandEntityInformation" xlink:type="simple" xlink:href="wynn-20240910.xsd#DocumentandEntityInformation"/>
  <link:presentationLink xlink:role="http://www.wynnresorts.com/role/DocumentandEntityInformation" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract_bb783100-af3e-4b25-93c0-7b52cedb7a4c" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_CoverAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_23567693-7ce0-46b0-8f43-2e995f749af0" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentType"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_bb783100-af3e-4b25-93c0-7b52cedb7a4c" xlink:to="loc_dei_DocumentType_23567693-7ce0-46b0-8f43-2e995f749af0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_adbe7b78-7130-4992-bc23-b68798ec82cf" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentPeriodEndDate"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_bb783100-af3e-4b25-93c0-7b52cedb7a4c" xlink:to="loc_dei_DocumentPeriodEndDate_adbe7b78-7130-4992-bc23-b68798ec82cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_ff47b22f-eee9-4e05-8d55-9de1e103424e" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityRegistrantName"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_bb783100-af3e-4b25-93c0-7b52cedb7a4c" xlink:to="loc_dei_EntityRegistrantName_ff47b22f-eee9-4e05-8d55-9de1e103424e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_2977a951-53c9-42e6-8494-a455ddacaf6a" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_bb783100-af3e-4b25-93c0-7b52cedb7a4c" xlink:to="loc_dei_EntityIncorporationStateCountryCode_2977a951-53c9-42e6-8494-a455ddacaf6a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_66a7972f-ff40-4297-ae62-7e63729c4582" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityFileNumber"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_bb783100-af3e-4b25-93c0-7b52cedb7a4c" xlink:to="loc_dei_EntityFileNumber_66a7972f-ff40-4297-ae62-7e63729c4582" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_bce30830-6078-4870-8eab-c9d72be71d6e" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_bb783100-af3e-4b25-93c0-7b52cedb7a4c" xlink:to="loc_dei_EntityTaxIdentificationNumber_bce30830-6078-4870-8eab-c9d72be71d6e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_8eb1438b-0af4-4f3b-a6fa-d21269e7f14e" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressAddressLine1"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_bb783100-af3e-4b25-93c0-7b52cedb7a4c" xlink:to="loc_dei_EntityAddressAddressLine1_8eb1438b-0af4-4f3b-a6fa-d21269e7f14e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_668448a2-487b-426a-86f3-75a81556c84f" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressCityOrTown"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_bb783100-af3e-4b25-93c0-7b52cedb7a4c" xlink:to="loc_dei_EntityAddressCityOrTown_668448a2-487b-426a-86f3-75a81556c84f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_20dfcecd-c0ea-4bf2-b267-cec97a501db5" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressStateOrProvince"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_bb783100-af3e-4b25-93c0-7b52cedb7a4c" xlink:to="loc_dei_EntityAddressStateOrProvince_20dfcecd-c0ea-4bf2-b267-cec97a501db5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_e4e87129-a573-4947-ba56-452e14d03b85" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressPostalZipCode"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_bb783100-af3e-4b25-93c0-7b52cedb7a4c" xlink:to="loc_dei_EntityAddressPostalZipCode_e4e87129-a573-4947-ba56-452e14d03b85" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_13ef6b30-aed6-44e4-bebf-2682e6b0bec7" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_CityAreaCode"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_bb783100-af3e-4b25-93c0-7b52cedb7a4c" xlink:to="loc_dei_CityAreaCode_13ef6b30-aed6-44e4-bebf-2682e6b0bec7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_c534a3fc-6c14-4096-8689-2c7a3bdc4820" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_LocalPhoneNumber"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_bb783100-af3e-4b25-93c0-7b52cedb7a4c" xlink:to="loc_dei_LocalPhoneNumber_c534a3fc-6c14-4096-8689-2c7a3bdc4820" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_7150227b-708c-4cb3-8ab3-9a1e971b0875" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_Security12bTitle"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_bb783100-af3e-4b25-93c0-7b52cedb7a4c" xlink:to="loc_dei_Security12bTitle_7150227b-708c-4cb3-8ab3-9a1e971b0875" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_e6c2d692-623a-4ca6-8936-42c6be57a881" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_TradingSymbol"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_bb783100-af3e-4b25-93c0-7b52cedb7a4c" xlink:to="loc_dei_TradingSymbol_e6c2d692-623a-4ca6-8936-42c6be57a881" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_5ed7c4f1-076b-4dcc-adb4-7bf65b44b866" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_SecurityExchangeName"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_bb783100-af3e-4b25-93c0-7b52cedb7a4c" xlink:to="loc_dei_SecurityExchangeName_5ed7c4f1-076b-4dcc-adb4-7bf65b44b866" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_WrittenCommunications_c1db79e6-40a1-4a25-97db-395249a0c972" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_WrittenCommunications"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_bb783100-af3e-4b25-93c0-7b52cedb7a4c" xlink:to="loc_dei_WrittenCommunications_c1db79e6-40a1-4a25-97db-395249a0c972" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SolicitingMaterial_d1c83e60-4272-4010-8c38-3de74939115d" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_SolicitingMaterial"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_bb783100-af3e-4b25-93c0-7b52cedb7a4c" xlink:to="loc_dei_SolicitingMaterial_d1c83e60-4272-4010-8c38-3de74939115d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementTenderOffer_068dee7f-e050-4903-8b85-12bce9ec1fd8" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_PreCommencementTenderOffer"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_bb783100-af3e-4b25-93c0-7b52cedb7a4c" xlink:to="loc_dei_PreCommencementTenderOffer_068dee7f-e050-4903-8b85-12bce9ec1fd8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementIssuerTenderOffer_13a58394-2b99-42b4-86e8-fd6c94576610" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_PreCommencementIssuerTenderOffer"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_bb783100-af3e-4b25-93c0-7b52cedb7a4c" xlink:to="loc_dei_PreCommencementIssuerTenderOffer_13a58394-2b99-42b4-86e8-fd6c94576610" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_a5ee9f84-436c-4b51-b30c-d63cb3203772" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_bb783100-af3e-4b25-93c0-7b52cedb7a4c" xlink:to="loc_dei_EntityEmergingGrowthCompany_a5ee9f84-436c-4b51-b30c-d63cb3203772" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_c57b933d-c53d-4f2b-93c3-cafb9a4097c9" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_AmendmentFlag"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_bb783100-af3e-4b25-93c0-7b52cedb7a4c" xlink:to="loc_dei_AmendmentFlag_c57b933d-c53d-4f2b-93c3-cafb9a4097c9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_03acf4bc-a61d-48b1-977e-f6d5bec02685" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityCentralIndexKey"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_bb783100-af3e-4b25-93c0-7b52cedb7a4c" xlink:to="loc_dei_EntityCentralIndexKey_03acf4bc-a61d-48b1-977e-f6d5bec02685" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
</link:linkbase>
