<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2026 Workiva-->
<!--r:01a15b7d-aa6d-78b5-9357-59139bc1b20f,g:fe3bb7fa-27c7-446d-b83d-516dbb08ad2e-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.wynnresorts.com/role/DocumentandEntityInformation" xlink:type="simple" xlink:href="wynn-20261023.xsd#DocumentandEntityInformation"/>
  <link:presentationLink xlink:role="http://www.wynnresorts.com/role/DocumentandEntityInformation" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_wynn_DEIAbstract_01a15b7d-aa6d-7662-bfb3-711132d2d68e" xlink:href="wynn-20261023.xsd#wynn_DEIAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_01a15b7d-aa6d-7361-8bf0-eb88f27a6aed" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_Security12bTitle"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_01a15b7d-aa6d-7662-bfb3-711132d2d68e" xlink:to="loc_dei_Security12bTitle_01a15b7d-aa6d-7361-8bf0-eb88f27a6aed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_01a15b7d-aa6d-711f-ae7f-fd9601df4ba4" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_01a15b7d-aa6d-7662-bfb3-711132d2d68e" xlink:to="loc_dei_EntityIncorporationStateCountryCode_01a15b7d-aa6d-711f-ae7f-fd9601df4ba4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_01a15b7d-aa6d-735e-8a6a-2f059e6c13a4" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityFileNumber"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_01a15b7d-aa6d-7662-bfb3-711132d2d68e" xlink:to="loc_dei_EntityFileNumber_01a15b7d-aa6d-735e-8a6a-2f059e6c13a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_01a15b7d-aa6d-779a-9ad3-40e283c7abe1" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_01a15b7d-aa6d-7662-bfb3-711132d2d68e" xlink:to="loc_dei_EntityTaxIdentificationNumber_01a15b7d-aa6d-779a-9ad3-40e283c7abe1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_01a15b7d-aa6d-7667-bd7e-f181e9fa1e2b" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressAddressLine1"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_01a15b7d-aa6d-7662-bfb3-711132d2d68e" xlink:to="loc_dei_EntityAddressAddressLine1_01a15b7d-aa6d-7667-bd7e-f181e9fa1e2b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_01a15b7d-aa6d-714b-bc98-1240b22d733b" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressCityOrTown"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_01a15b7d-aa6d-7662-bfb3-711132d2d68e" xlink:to="loc_dei_EntityAddressCityOrTown_01a15b7d-aa6d-714b-bc98-1240b22d733b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_01a15b7d-aa6d-7bfc-a833-3e9314df64eb" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressStateOrProvince"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_01a15b7d-aa6d-7662-bfb3-711132d2d68e" xlink:to="loc_dei_EntityAddressStateOrProvince_01a15b7d-aa6d-7bfc-a833-3e9314df64eb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_01a15b7d-aa6d-7cb5-aaef-60dc23a7025f" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_DocumentType"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_01a15b7d-aa6d-7662-bfb3-711132d2d68e" xlink:to="loc_dei_DocumentType_01a15b7d-aa6d-7cb5-aaef-60dc23a7025f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_01a15b7d-aa6d-7119-ae9e-9abce9792fab" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityRegistrantName"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_01a15b7d-aa6d-7662-bfb3-711132d2d68e" xlink:to="loc_dei_EntityRegistrantName_01a15b7d-aa6d-7119-ae9e-9abce9792fab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_01a15b7d-aa6d-7d58-90cf-bdef13dd6b1b" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityCentralIndexKey"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_01a15b7d-aa6d-7662-bfb3-711132d2d68e" xlink:to="loc_dei_EntityCentralIndexKey_01a15b7d-aa6d-7d58-90cf-bdef13dd6b1b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_01a15b7d-aa6d-715b-a1e1-fdef34ca3436" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_DocumentPeriodEndDate"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_01a15b7d-aa6d-7662-bfb3-711132d2d68e" xlink:to="loc_dei_DocumentPeriodEndDate_01a15b7d-aa6d-715b-a1e1-fdef34ca3436" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_01a15b7d-aa6d-76c4-94dc-15403be85436" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressPostalZipCode"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_01a15b7d-aa6d-7662-bfb3-711132d2d68e" xlink:to="loc_dei_EntityAddressPostalZipCode_01a15b7d-aa6d-76c4-94dc-15403be85436" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_01a15b7d-aa6d-768f-bd7b-7ff3f111fc04" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_CityAreaCode"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_01a15b7d-aa6d-7662-bfb3-711132d2d68e" xlink:to="loc_dei_CityAreaCode_01a15b7d-aa6d-768f-bd7b-7ff3f111fc04" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_01a15b7d-aa6d-74b4-9a32-aa2496640f65" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_LocalPhoneNumber"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_01a15b7d-aa6d-7662-bfb3-711132d2d68e" xlink:to="loc_dei_LocalPhoneNumber_01a15b7d-aa6d-74b4-9a32-aa2496640f65" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_WrittenCommunications_01a15b7d-aa6d-7b08-98a5-a6321ecbaee0" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_WrittenCommunications"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_01a15b7d-aa6d-7662-bfb3-711132d2d68e" xlink:to="loc_dei_WrittenCommunications_01a15b7d-aa6d-7b08-98a5-a6321ecbaee0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_01a15b7d-aa6d-75eb-83b7-e9ccecd1c5f9" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_TradingSymbol"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_01a15b7d-aa6d-7662-bfb3-711132d2d68e" xlink:to="loc_dei_TradingSymbol_01a15b7d-aa6d-75eb-83b7-e9ccecd1c5f9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_01a15b7d-aa6d-7e80-8876-1d44923d3ac6" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_SecurityExchangeName"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_01a15b7d-aa6d-7662-bfb3-711132d2d68e" xlink:to="loc_dei_SecurityExchangeName_01a15b7d-aa6d-7e80-8876-1d44923d3ac6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SolicitingMaterial_01a15b7d-aa6d-737e-acbb-530c9d8d6382" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_SolicitingMaterial"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_01a15b7d-aa6d-7662-bfb3-711132d2d68e" xlink:to="loc_dei_SolicitingMaterial_01a15b7d-aa6d-737e-acbb-530c9d8d6382" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementTenderOffer_01a15b7d-aa6d-758e-9fdf-e3e17a6bbf8e" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_PreCommencementTenderOffer"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_01a15b7d-aa6d-7662-bfb3-711132d2d68e" xlink:to="loc_dei_PreCommencementTenderOffer_01a15b7d-aa6d-758e-9fdf-e3e17a6bbf8e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementIssuerTenderOffer_01a15b7d-aa6d-74de-b4bd-9a65ac7cf2e1" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_PreCommencementIssuerTenderOffer"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_01a15b7d-aa6d-7662-bfb3-711132d2d68e" xlink:to="loc_dei_PreCommencementIssuerTenderOffer_01a15b7d-aa6d-74de-b4bd-9a65ac7cf2e1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_01a15b7d-aa6d-7f97-8ae5-5370b132312d" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_01a15b7d-aa6d-7662-bfb3-711132d2d68e" xlink:to="loc_dei_EntityEmergingGrowthCompany_01a15b7d-aa6d-7f97-8ae5-5370b132312d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_01a15b7d-aa6d-7736-92ba-bb0297613545" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_AmendmentFlag"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_01a15b7d-aa6d-7662-bfb3-711132d2d68e" xlink:to="loc_dei_AmendmentFlag_01a15b7d-aa6d-7736-92ba-bb0297613545" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
</link:linkbase>
