<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2025 Workiva-->
<!--r:5db2a100-069a-4271-9567-ee8105f91d24,g:b73f9c81-46eb-4487-bbee-5ebf2f474348-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.wynnresorts.com/role/DocumentandEntityInformation" xlink:type="simple" xlink:href="wynn-20250602.xsd#DocumentandEntityInformation"/>
  <link:presentationLink xlink:role="http://www.wynnresorts.com/role/DocumentandEntityInformation" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_wynn_DEIAbstract_f1bf27a5-5d85-4a03-b120-0f4afd31ad0e" xlink:href="wynn-20250602.xsd#wynn_DEIAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_bad223b5-5f11-47e1-9579-38805a75e657" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_Security12bTitle"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_f1bf27a5-5d85-4a03-b120-0f4afd31ad0e" xlink:to="loc_dei_Security12bTitle_bad223b5-5f11-47e1-9579-38805a75e657" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_115a2840-ab2a-4339-af68-3a349e8c9f95" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_f1bf27a5-5d85-4a03-b120-0f4afd31ad0e" xlink:to="loc_dei_EntityIncorporationStateCountryCode_115a2840-ab2a-4339-af68-3a349e8c9f95" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_aae0e811-3a69-48ec-897d-54df362dad6f" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityFileNumber"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_f1bf27a5-5d85-4a03-b120-0f4afd31ad0e" xlink:to="loc_dei_EntityFileNumber_aae0e811-3a69-48ec-897d-54df362dad6f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_ac446e77-93b3-43b4-9acf-91aae001689e" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_f1bf27a5-5d85-4a03-b120-0f4afd31ad0e" xlink:to="loc_dei_EntityTaxIdentificationNumber_ac446e77-93b3-43b4-9acf-91aae001689e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_0caa937b-2faf-442d-b7bb-398873555109" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressAddressLine1"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_f1bf27a5-5d85-4a03-b120-0f4afd31ad0e" xlink:to="loc_dei_EntityAddressAddressLine1_0caa937b-2faf-442d-b7bb-398873555109" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_b882a334-6599-49ba-bdeb-793b814d59ff" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressCityOrTown"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_f1bf27a5-5d85-4a03-b120-0f4afd31ad0e" xlink:to="loc_dei_EntityAddressCityOrTown_b882a334-6599-49ba-bdeb-793b814d59ff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_4b368387-3c53-4914-8288-5b1d26327297" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressStateOrProvince"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_f1bf27a5-5d85-4a03-b120-0f4afd31ad0e" xlink:to="loc_dei_EntityAddressStateOrProvince_4b368387-3c53-4914-8288-5b1d26327297" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_1c35cc41-9540-40fc-9076-04c366e1e44b" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentType"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_f1bf27a5-5d85-4a03-b120-0f4afd31ad0e" xlink:to="loc_dei_DocumentType_1c35cc41-9540-40fc-9076-04c366e1e44b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_e48299b7-0f63-4cf1-905d-4f011d68d904" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityRegistrantName"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_f1bf27a5-5d85-4a03-b120-0f4afd31ad0e" xlink:to="loc_dei_EntityRegistrantName_e48299b7-0f63-4cf1-905d-4f011d68d904" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_a8393079-d2b3-476c-b30c-880dcd4617da" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityCentralIndexKey"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_f1bf27a5-5d85-4a03-b120-0f4afd31ad0e" xlink:to="loc_dei_EntityCentralIndexKey_a8393079-d2b3-476c-b30c-880dcd4617da" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_392e1d24-3f74-4403-b385-76df75b72193" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentPeriodEndDate"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_f1bf27a5-5d85-4a03-b120-0f4afd31ad0e" xlink:to="loc_dei_DocumentPeriodEndDate_392e1d24-3f74-4403-b385-76df75b72193" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_6898ecee-f013-468a-8446-df588c1714da" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressPostalZipCode"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_f1bf27a5-5d85-4a03-b120-0f4afd31ad0e" xlink:to="loc_dei_EntityAddressPostalZipCode_6898ecee-f013-468a-8446-df588c1714da" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_87b66c5c-8b9f-4353-a412-5e30a60efecc" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_CityAreaCode"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_f1bf27a5-5d85-4a03-b120-0f4afd31ad0e" xlink:to="loc_dei_CityAreaCode_87b66c5c-8b9f-4353-a412-5e30a60efecc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_be77c8e0-2a45-48b7-b975-ff3c49096ea1" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_LocalPhoneNumber"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_f1bf27a5-5d85-4a03-b120-0f4afd31ad0e" xlink:to="loc_dei_LocalPhoneNumber_be77c8e0-2a45-48b7-b975-ff3c49096ea1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_WrittenCommunications_52c823e4-0a2c-44fa-bb0b-cb8faea3d1c8" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_WrittenCommunications"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_f1bf27a5-5d85-4a03-b120-0f4afd31ad0e" xlink:to="loc_dei_WrittenCommunications_52c823e4-0a2c-44fa-bb0b-cb8faea3d1c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_b5c9be14-c2b9-497d-bc82-abc875c60339" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_TradingSymbol"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_f1bf27a5-5d85-4a03-b120-0f4afd31ad0e" xlink:to="loc_dei_TradingSymbol_b5c9be14-c2b9-497d-bc82-abc875c60339" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_36b843c2-9836-4788-b5f6-787a69a664a7" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_SecurityExchangeName"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_f1bf27a5-5d85-4a03-b120-0f4afd31ad0e" xlink:to="loc_dei_SecurityExchangeName_36b843c2-9836-4788-b5f6-787a69a664a7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SolicitingMaterial_67e1d5df-7ef8-46bc-acc0-10705363acf0" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_SolicitingMaterial"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_f1bf27a5-5d85-4a03-b120-0f4afd31ad0e" xlink:to="loc_dei_SolicitingMaterial_67e1d5df-7ef8-46bc-acc0-10705363acf0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementTenderOffer_cc470e35-aa2a-4205-86d2-9279c437d4fb" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_PreCommencementTenderOffer"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_f1bf27a5-5d85-4a03-b120-0f4afd31ad0e" xlink:to="loc_dei_PreCommencementTenderOffer_cc470e35-aa2a-4205-86d2-9279c437d4fb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementIssuerTenderOffer_0fa8beec-278f-49c4-a44d-333f45149dae" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_PreCommencementIssuerTenderOffer"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_f1bf27a5-5d85-4a03-b120-0f4afd31ad0e" xlink:to="loc_dei_PreCommencementIssuerTenderOffer_0fa8beec-278f-49c4-a44d-333f45149dae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_42307444-37ea-4708-9189-b2c92e751d96" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_f1bf27a5-5d85-4a03-b120-0f4afd31ad0e" xlink:to="loc_dei_EntityEmergingGrowthCompany_42307444-37ea-4708-9189-b2c92e751d96" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_fe007262-456a-4237-9d7f-2001107275c2" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_AmendmentFlag"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_wynn_DEIAbstract_f1bf27a5-5d85-4a03-b120-0f4afd31ad0e" xlink:to="loc_dei_AmendmentFlag_fe007262-456a-4237-9d7f-2001107275c2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
</link:linkbase>
